Targeting SMC3 deacetylation synergizes with XPO1 inhibition to reprogram the epigenetic landscape and suppress NPM1-mutated acute myeloid leukemia
Fu Jianfeng, Xu Huilin, Zhao Xinying, Gao Mengge, Tian Yonglu, Chang Yingjun, Zheng Xiaofeng
Journal：Nature Communications
IF：18.1
DOI：10.1038/s41467-026-74343-y
PMID：
Published：2026-06-11
research field：肿瘤学分子生物学血液学癌症治疗学表观遗传学
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