Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.
高纯度、高活性、低内毒素、高批间一致性
SDS-PAGE
Human Latent Activin A on Bis-Tris PAGE under reduced (R) condition. The purity is greater than 95%.
ELISA Data
Immobilized Human Latent Activin A, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 16.6ng/ml determined by ELISA.
-25 ~ -15℃保存，收到货之后有效期1年。
复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。
