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分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
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抑制剂激活剂与常用试剂
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Anti-IL-6Ra / CD126 Reference Antibody (tocilizumab)
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产品介绍

Tocilizumab,一种抗人IL-6R的人源化抗体,能够靶向人白细胞介素-6受体(IL-6R),阻断IL-6与IL-6R的结合,从而抑制经典信号通路和反式信号通路,可用于类风湿关节炎的相关研究。

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应用案例

Purity:SDS-PAGE

Anti-IL-6Ra / CD126 Reference Antibody (tocilizumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

Purity:SEC-HPLC

The purity of Anti-IL-6Ra / CD126 Reference Antibody (tocilizumab) is more than 95%, determined by SEC-HPLC.

Bioactivity:FACS

Human IL-6R CHOs cells were stained with Anti-IL-6Ra / CD126 Reference Antibody (tocilizumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.4525 nM.

Function:Blocking

Anti-IL-6Ra / CD126 Reference Antibody (tocilizumab)-induced FACS Blocking activity was evaluated using Human IL-6R CHO cells. The IC50 was approximately 1.303nM.

存储条件

-25~-15℃保存,有效期1年。

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