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This gene is predominantly expressed in the Tis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Western

Western blot analysis of NOX5 in 293T, hela, Human testis, SKOV-3, Raji, Jurkat lysates using NOX5 antibody

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human liver cancer using NOX5 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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