This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Western
Western blot analysis of CD1A in Hela (1), HepG2 (2), HEK293 (3),MOLT4 (4),K562 (5),HEK293-6e (6),Cos-7 (7),and NIH/3T3 (8) cell lysate using CD1A antibody.
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded human bladder cancer tissues using CD1A antibody.
Immunocytochemistry
Immunocytochemistry analysis of CD1A in Hela cells using CD1A antibody (green),and DAPI(blue). Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Flow
Flow Cytometry analysis of K562 cells using CD1A antibody (green) and negative control (red).
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