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NGFR Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR- associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1.

Western

Western blot analysis of p75 NGF Receptor in PC12 lysates using p75 NGF Receptor antibody.

Western

Western blot analysis of NGFR in (1) C6 lysates; (2) PC-12 lysates using NGFR antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human glioma using NGFR antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。