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The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of WIF1 in Hela lysates using WIF1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human esophagus cancer using WIF1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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