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Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200

Western blot analysis of CD86 in THP-1 lysates using CD86 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using CD86 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of CD86 in MCF-7 cells using CD86 antibody,and DAPI (blue).

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