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Act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200;IP:1/20

Immunocytochemistry analysis of ERK2 (green) in K562 using ERK2 antibody,and DAPI(blue).

Western blot analysis of ERK2 in K562, rat Brain, C6, 3T3, Hela lysates using ERK2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using ERK2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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