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Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3), and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy. Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of LC3A (8F5)in Hela lysates, 3T3 lysates, rat Brain lysates using LC3A antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。