The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
推荐稀释比 IHC:1/50-1/100
Immunohistochemistry analysis of paraffin-embedded human prostate cancer using Syntenin 1 antibbody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded human melanoma cases using Syntenin 1 antibbody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
