CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.
Flow Cytometry analysis of C57BL/6 murine splenocytes stained with CD45.2 antibody (FITC).Unstained splenocytes (empty black histogram) are used as control.
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
