Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
推荐稀释比 WB:1/1000-1/2000; IHC:1/100-1/200; IF:1/50-1/200; FC:1/50-1/100
Western blot analysis of alpha smooth muscle Actin in (1)A549 lysates; (2)C2C12 lysates using alpha Smooth Muscle Actin antibody.
Immunohistochemistry analysis of paraffin-embedded Human colon using alpha smooth muscle Actin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunofluorescence analysis of alpha Smooth Muscle Actin in A431 using alpha smooth muscle Actin antibody.
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
