3522集团新网站

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

推荐稀释比 WB:1/500-1/1000; IHC:1/50-1/100; IF:1/100-1/500

Western blot analysis of Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199) in 293 lysates untreated or treated with sorbitol using Phospho-PI3 Kinase p85/p55 (Tyr467/Tyr199) antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。