Zotatifin (eFT226)能诱导细胞凋亡并具有强效抗病毒活性。作为一种高效的eIF4A抑制剂，它通过促进eIF4A与特定mRNA结合、干扰eIF4F组装，进而抑制SARS-CoV-2 NP蛋白合成。
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