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作为 Tolterodine的活性代谢物，(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) hydrochloride 凭借其 mAChR 拮抗活性，在膀胱过度活动症研究中展现出潜在用途。

[1] Malhotra B, Gandelman K, Sachse R, Wood N, Michel MC. The design and development of fesoterodine as a prodrug of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of tolterodine. Curr Med Chem. 2009;16(33):4481-9. doi: 10.2174/092986709789712835. PMID: 19835561.[2]Yamada S, Kuraoka S, Ito Y, Kato Y, Onoue S. Muscarinic receptor binding of fesoterodine, 5-hydroxymethyl tolterodine, and tolterodine in rat tissues after the oral, intravenous, or intravesical administration. J Pharmacol Sci. 2019 May;140(1):73-78. doi: 10.1016/j.jphs.2019.05.001. Epub 2019 May 18. PMID: 31153768.