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N6-Cyclopentyladenosine (CPA)是一种选择性腺苷 A1 受体激动剂，对人 A1、A2A 和 A3 受体的 Ki 值分别为 2.3 nM、790 nM 和 43 nM。CPA 可促进细胞凋亡，并表现出抗白血病肿瘤活性。此外，它还能改善 5-fluorouracil 所致的造血损伤、调节睡眠，并延缓 Aminophylline 诱发的阵挛性癫痫发作。

[1] Mlejnek P, Dolezel P. Apoptosis induced by N6-substituted derivatives of adenosine is related to intracellular accumulation of corresponding mononucleotides in HL-60 cells. Toxicol In Vitro. 2005 Oct;19(7):985-90. doi: 10.1016/j.tiv.2005.06.023. Epub 2005 Sep 21. PMID: 16181767.[2]Jaishree J, Kumaresan S, Sudha S, David J, Kulkarni C. Individual and combined effects of N6-cyclopentyladenosine, flunarizine and diazepam on aminophylline-induced recurrent generalized seizures in mice. Pol J Pharmacol. 2003 Jul-Aug;55(4):559-64. PMID: 14581714.