Human PAcP is classically known as a prostate epithelium-specific 100 kDa glycoprotein, consisting of two subunits with molecular weight of about 50 kDa each. In normal differentiated prostate epithelia, PAcP protein can be detected intracellularly as the cellular form (cPAcP) and in seminal fluid as the secretory form (sPAcP). The two forms of PAcP protein are apparently transcribed from the same gene followed by different post-transcriptional modifications. Circulating PAcP activity is serving as a surrogate marker for diagnosing PCa as well as for evaluating the efficacy of ADT for advanced PCa.
高活性、高纯度、低内毒素、高稳定性
SDS-PAGE
Human Prostatic Acid Phosphatase on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Human Prostatic Acid Phosphatase is greater than 95% as determined by SEC-HPLC.
Bioactivity Data
Measured by its ability to cleave a substrate, p-Nitrophenyl phosphate (pNPP). The specific activity is >90000 pmol/min/ug.
-85 ~ -65℃保存，收到货之后有效期1年。 避免反复冻融，打开小瓶前先离心。建议等分分装为一次实验使用量，分装后，-80℃冻存。
