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Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).

稀释比 WB: 1/2000-5000 ICC: 1/100-500 IP: 1/200 IHC: 1/50-300

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。

Q：该抗体的免疫原用的是什么？

A：免疫原用的是全长蛋白。