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As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.

推荐稀释比 WB: 1/500-1/1000  IHC: 1/50-1/100  IP: 1/20

Western

Western blot analysis of RPA32/RPA2 in 3T3 lysates using RPA32 antibody.

Western

Western blot analysis of RPA32/RPA2 in Hela, CHO-K1, C6, Jurkat lysates using RPA32/RPA2 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil using RPA32/RPA2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。