Pimecrolimus (SDZ-ASM 981)是一种口服有效的非甾体抗炎化合物,通过抑制钙调磷酸酶发挥作用。
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英文别名 (English Synonym) |
Pimecrolimus |
|
中文名称 (Chinese Name) |
吡美莫司 |
|
靶点 (Target) |
|
|
通路 (Pathway) |
Immunology/Inflammation |
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CAS号 (CAS NO.) |
137071-32-0 |
|
分子式 (Formula) |
C43H68ClNO11 |
|
分子量 (Molecular Weight) |
810.45 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Grassberger M, Baumruker T, Enz A, Hiestand P, Hultsch T, Kalthoff F, Schuler W, Schulz M, Werner FJ, Winiski A, Wolff B, Zenke G. A novel anti-inflammatory drug, SDZ ASM 981, for the treatment of skin diseases: in vitro pharmacology. Br J Dermatol. 1999 Aug,141(2):264-73. doi: 10.1046/j.1365-2133.1999.02974.x. PMID: 10468798.[2]Meingassner JG, Grassberger M, Fahrngruber H, Moore HD, Schuurman H, Stütz A. A novel anti-inflammatory drug, SDZ ASM 981, for the topical and oral treatment of skin diseases: in vivo pharmacology. Br J Dermatol. 1997 Oct,137(4):568-76. doi: 10.1111/j.1365-2133.1997.tb03788.x. PMID: 9390333.
