Azelastine hydrochloride是一种用于过敏性鼻炎、哮喘、糖尿病高脂血症及SARS-CoV-2研究的药物,属于选择性组胺H1受体拮抗剂类抗组胺剂。
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英文别名 (English Synonym) |
Azelastine HCl |
|
中文名称 (Chinese Name) |
盐酸氮卓斯汀 |
|
靶点 (Target) |
Histamine Receptor |
|
通路 (Pathway) |
Neuroscience |
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CAS号 (CAS NO.) |
79307-93-0 |
|
分子式 (Formula) |
C22H24ClN3O·HCl |
|
分子量 (Molecular Weight) |
418.36 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Liu SC, Lin CS, Chen SG, Chu YH, Lee FP, Lu HH, Wang HW. Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells. Eur Arch Otorhinolaryngol. 2017 Feb,274(2):845-853. doi: 10.1007/s00405-016-4295-8. Epub 2016 Sep 13. PMID: 27623823.[2]Elseweidy MM, Elnagar GM, Elsawy MM, Zein N. Azelastine a potent antihistamine agent, as hypolipidemic and modulator for aortic calcification in diabetic hyperlipidemic rats model. Arch Physiol Biochem. 2022 Dec,128(6):1611-1618. doi: 10.1080/13813455.2020.1786129. Epub 2020 Jul 2. PMID: 32615812.
