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GDF-15 is a cytokine protein belonging to the TGF-β superfamily. It is widely expressed in the human body, including in tissues such as the liver, heart, kidneys, lungs, intestines, muscles, brain, and pancreas. The expression of GDF-15 is regulated by various physiological and pathological conditions, such as inflammation, tumors, cardiovascular diseases, and metabolic disorders.

GDF-15 plays an important role in physiological processes such as cell proliferation, apoptosis, inflammation, and metabolism. It is considered an important inflammatory marker, playing a crucial role in inflammatory responses and immune reactions. Additionally, GDF-15 has been found to be closely associated with the occurrence, development, and metastasis of tumors, affecting tumor growth by regulating cell proliferation, apoptosis, invasion, and metastasis pathways. In recent years, research has revealed that GDF-15 is also linked to many other diseases such as cardiovascular diseases, metabolic syndrome, diabetes, and kidney diseases. Therefore, GDF-15 has become a research hotspot and is widely used in aspects like disease diagnosis, prognosis assessment, and treatment monitoring.

高纯度、高活性、低内毒素、高批间一致性

SDS-PAGE

Figure 1.On SDS-PAGE non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA

Figure 2.Human pro-GDF15 Protein; His Tag was immobilized at 1 μg/ml (100 μL/well). Increasing concentrations of Anti-GDF15 hIgG1 Reference Antibody were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。