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GFR alpha like is a protein associated with the Glial Cell Line-Derived Neurotrophic Factor Receptor (GFR). It is a cell surface receptor closely linked to the binding and signal transduction of the GDNF family of neurotrophic factors (GDNF, NRTN, ARTN, and PSPN). The GFR alpha like protein plays a crucial role in the development and maintenance of the nervous system, regulating processes such as neuronal survival, differentiation, migration, and synapse formation. Research indicates that the expression of GFR alpha like protein in the nervous system is associated with various neurological diseases and disease models, potentially playing a role in the pathogenesis of neurodegenerative diseases. Further research into the function and regulatory mechanisms of GFR alpha like protein can help deepen our understanding of the occurrence and development of neurological diseases, providing new targets and strategies for the treatment of related diseases.

高纯度、高活性、低内毒素、高批间一致性

SDS-PAGE

Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA

Figure 2.Human GDF15 Protein; His Tag was immobilized at 1 μg/ml (100 μL/well). Increasing concentrations of Human GFRAL Protein; hFc Tag were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。