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Musk protein (Muscle-specific Kinase, MUSK) is a tyrosine kinase specifically expressed in muscle tissue, primarily involved in the development and maintenance of neuromuscular junctions. MUSK plays a key role in synapse formation by promoting the formation and stability of synapses through its interaction with nerve growth factors released by neurons.

MUSK plays an important role in the development of neuromuscular junctions by interacting with proteins on the neuronal membrane, facilitating the clustering of receptors on the muscle cell membrane. MUSK activates various signaling pathways, regulating the functions and growth of muscle cells. MUSK also plays a crucial role in the differentiation and growth of muscle cells, influencing the muscle development process.

Abnormalities in MUSK may be associated with certain diseases, such as myasthenia syndrome, making research on MUSK helpful for understanding related physiological and pathological mechanisms. Scientists are exploring the potential of MUSK as a therapeutic target, particularly in the treatment of neuromuscular diseases.

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SDS-PAGE

Figure 1. On SDS-PAGE under nun-reducing (NR) condition and reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA

Figure 2.Rat MUSK Protein; mFc Tag was immobilized at 2 μg/ml (100 μL/well). Increasing concentrations of Anti-MUSK hIgG1 Antibody were added.

-85 ~ -65℃保存，收到货之日起，6个月有效期。避免反复冻融，建议等分分装为一次实验使用量，分装后，-80℃冻存。