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Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes.

推荐稀释比 WB: 1/500-1/1000  IHC: 1/50-1/100  IF: 1/50-1/200

Western

Western blot analysis of KAP1 in K562, C6, 3T3, Hela lysates using KAP1 antibody.

Immunocytochemistry

Immunocytochemistry analysis of KAP1(green) in Hela using KAP1 antibody,and DAPI(blue)

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using KAP1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。